COMPANY OVERVIEW

The Company was formed in 1986 to develop and provide diagnostic products and services. During the 1990’s, we developed, manufactured and marketed a line of specialty biological products targeting a niche market in pituitary hormone and tumor marker diagnostic testing. While the original manufacturing methods involved the extraction and purification of products from human tissues, we also conducted research into methods of cellular immortalization, involving genetic engineering of differentiated cells to generate immortalized cell lines that maintained characteristics of differentiated cells including hormone production. This technology allows use of the cell lines as the raw material necessary for the manufacture of purified hormones instead of requiring a source of human tissues. In 2000, we sold the diagnostic antigen business to AspenBio Pharma, Inc. and the Company maintained its focus on cell line development, related technologies and products.